Our research efforts are aimed at the development of the imaging mass spectrometry (IMS) technology which allows us to simultaneoulsy map the localization of hundreds of different biocompounds (peptides, proteins, lipids and other metabolites as well as administered pharmaceuticals) present in thin tissue sections through the use of matrix-assisted laser desorption ionization (MALDI) as the means of ion production and time-of-flight (TOF) mass analyzers for ion detection.
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The research group consists of a dynamic mix of graduate and post-graduate researchers from a diverse range of scientific backgrounds. Alumni from the group continue to greatly contribute to our research efforts.
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Our laboratory is one of the few in Canada that has access to a MALDI system dedicated to imaging mass spectrometry (IMS). Our laboratory is also equipped with a cryostat, an ImagePrep, a TM Sprayer, a CHIP-1000 Chemical Inkjet Printer, a sublimation system, and a tissue staining station that are necessary in the sample preparation process, and a state-of-the-art desktop computers for data-analysis post data acquisition.
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In the past five years, the group has produced over 25 publications, including over 20 peer-reviewed articles. Publication topics range from mass spectrometry method development to tissue imaging applications.
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