Publications
Below are publications produced by members of the group since 2011.
Peer-reviewed Publications
2023
- Metal-assisted laser desorption ionization imaging mass spectrometry for biological and forensic applications F. Fournelle*, N. Lauzon*, E. Yang*, and P. Chaurand* Microchemical Journal, Vol. 185 (2023) DOI https://doi.org/10.1016/j.microc.2022.108294
2022
- Absolute quantification of cholesterol from thin tissue sections by silver-assisted laser desorption ionization mass spectrometry imaging Z.S. Nezhad*, J.P. Salazar*, R.S. Pryce*, L.M. Munter, and P. Chaurand*. Analytical and Bioanalytical Chemistry, Vol. 414, Iss. 23, 6947-6954 (2022) DOI 10.1007/s00216-022-04262-6
- The cholesteryl ester transfer protein (CETP) raises cholesterol levels in the brain and affects presenilin-mediated gene regulation F. Oestereich, N. Yousefpour, E. Yang*, A. Ribeiro-da-Silva, P. Chaurand*, L.M. Munter. Journal of Lipid Research, Vol. 63, Iss. 9 (2022) DOI 10.1016/j.jlr.2022.100260HTML
2021
- Visualizing the distribution of strawberry plant metabolites at different maturity stages by MALDI-TOF imaging mass spectrometry J. Wang, E. Yang*, P. Chaurand*, V. Raghavan. Food Chemistry, Vol. 345 (2021) DOI 10.1016/j.foodchem.2020.128838
- A matrix‐assisted laser desorption/ionization imaging mass spectrometric approach to study weight‐related changes within thyroid tissue A.A. Alfadda, H. Benabdelkamel, A.A. Fathaddin, I.O. Alanazi, N. Lauzon, P. Chaurand*, A. Masood. Journal of Mass Spectrometry, Vol. 56, e4671 (2021) DOI 10.1002/jms.4671HTML
2020
- Probiotics Modulate a Novel Amphibian Skin Defense Peptide that is both Antifungal and Facilitates Growth of Antifungal Bacteria. D.C. Woodhams, L.A. Rollins-Smith, L.K. Reinert, B.A. Lam, R.N. Harris, C.J. Briggs, V.T. Vredenburg, B.T. Patel, R.M. Caprioli, P. Chaurand, P. Hunziker and L. Bigler. Microbial Ecology, Vol. 79, 192-202 (2020). DOI 10.1007/s00248-019-01385-9
- Silver spray deposition for AgLDI imaging MS of cholesterol and other olefins on thin tissue sections E. Yang*, F. Fournelle* and P. Chaurand*. Journal of Mass Spectrometry, Special Issue, Vol. 55, e4428 (2020) DOI 10.1002/jms.4428HTML
- Minimizing Visceral Fat Delocalization on Tissue Sections with Porous Aluminum Oxide Slides for Imaging Mass Spectrometry F. Fournelle*, E. Yang*, M. Dufresne* and P. Chaurand*. Analytical Chemistry, Vol. 92, 5158-5167 (2020) DOI 10.1021/acs.analchem.9b05665HTML
- rMSIcleanup: an open-source tool for matrix-related peak annotation in mass spectrometry imaging and its application to silver-assisted laser desorption/ionization G. Baquer, L. Sementé, M. García-Altares, Y-J. Lee, P. Chaurand*, X. Correig and P. RàfolsJournal of Cheminformatics, Vol. 12, 45 (2020) DOI 10.1186/s13321-020-00449-0HTML
- Multimodal Imaging Mass Spectrometry to Identify Markers of Pulmonary Arterial Hypertension in Human Lung Tissue using MALDI-ToF, ToF-SIMS and Hybrid SIMS S. Van Nuffel, M. Quatredeniers, A. Pirkl, J. Zakel, J-P. Le Caer, N. Elie, Q. Vanbellingen, S. Dumas, M. Nakhleh, M. Ghigna, E. Fadel, M. Humbert, P. Chaurand*, D. Touboul, S. Cohen-Kaminsky and A. Brunelle. Analytical Chemistry, Vol. 92, 12079-12087 (2020) DOI 10.1002/jms.4671HTML
2019
- Mild Methylenetetrahydrofolate Reductase Deficiency Alters Inflammatory and Lipid Pathways in Liver. D. Leclerc, K. Christensen, O. Cauv, E. Yang*, F. Fournelle*, R. Bahous, O. Malysheva, L. Deng, Q. Wu, Z. Zhou, Z.-H. Gao, P. Chaurand, M. A. Caudill and R. Rozen. Molecular Nutrition and Food Research, Vol 63, 1801001 (2019). DOI 10.1002/mnfr.201801001HTML
- Mapping the triglyceride distribution in NAFLD human liver by MALDI imaging mass spectrometry reveals molecular differences in micro and macro steatosis. H. Alarmi, N. H. Patterson, E. Yang*, P. Zoroquiain, A. Lazaris, P. Chaurand and P. Metrakos. Analytical and Bioanalytical Chemistry, Vol 411, 885-894 (2019). DOI 10.1007/s00216-018-1506-8HTML
- Enhancing ganglioside species detection for MALDI-TOF imaging mass spectrometry in negative reflectron mode. E. Yang*, M. Dufresne*, and P. Chaurand* International Journal of Mass Spectrometry, Vol. 437, 3-9 (2019). DOI 10.1016/j.ijms.2017.09.011HTML
- Co-registration and analysis of multiple imaging mass spectrometry datasets targeting different analytes. N.H. Patterson*, E. Yang*, E.-A. Kranjec* and P. Chaurand*. Bioinformatics, Vol. 35, 1261-1262 (2019). DOI 10.1093/bioinformatics/bty780HTML
- Mapping the fly Malpighian tubule lipidome by imaging mass spectrometry E. Yang*, C. Gamberi and P. Chaurand*. Journal of Mass Spectrometry, Vol. 54, 557-566 (2019). DOI 10.1002/jms.4366HTML
2018
- Insights into the MALDI Process after Matrix Deposition by Sublimation Using 3D ToF-SIMS Imaging. S. Van Nuffel, N. Elie, E. Yang*, J. Nouet, D. Touboul, P. Chaurand* and A. Brunelle. Analytical Chemistry, Vol. 90, 1907–1914 (2018). DOI 10.1021/acs.analchem.7b03993HTML
- Detection of exogenous substances in latent fingermarks by silver-assisted LDI imaging MS: perspectives in forensic sciences. N. Lauzon* and P. Chaurand*. Analyst, Vol. 143, 3586-3594 (2018). DOI 10.1039/c8an00688aHTML
2017
- Multimodal detection of GM2 and GM3 lipid species in the brain of mucopolysaccharidosis type II mouse by serial imaging mass spectrometry and immunohistochemistry M. Dufresne*, D. Guneysu*, N.H. Patterson*, M.M. Marcinkiewicz, A. Regina, M. Demeule and P. Chaurand* Analytical and Bioanalytical Chemistry, Vol. 409, 1425-1433 (2017). DOI 10.1007/s00216-016-0076-xHTML
- Forensic analysis of latent fingermarks by silver-assisted LDI imaging MS on non-conductive surfaces. N. Lauzon*, M. Dufresne*, A. Beaudoin and P. Chaurand* Journal of Mass Spectrometry, Vol. 52, 397-404 (2017). DOI https://doi.org/10.1002/jms.3865HTML
2016
- Surface Plasmon Resonance imaging - MALDI-TOF imaging mass spectrometry (SPRi - MALDI IMS) of thin tissue sections. S. Forest*, J. Breault-Turcot, P. Chaurand* and J-F. Masson. Analytical Chemistry, Vol. 88, 2072-2079 (2016). DOI 10.1021/acs.analchem.5b03309HTML
- Three-dimensional imaging MS of lipids in atherosclerotic plaques: Open-source methods for reconstruction and analysis. N.H. Patterson*, R.J. Doonan, S.S. Daskalopoulou, M. Dufresne*, S. Lenglet, F. Montecucco, A. Thomas* and P. Chaurand*. Proteomics, Vol. 16, 1642-1651 (2016). DOI 10.1002/pmic.201500490HTML
- Sodium-Doped Gold-Assisted Laser Desorption Ionization for Enhanced Imaging Mass Spectrometry of Triacylglycerols from Thin Tissue Sections. M. Dufresne*, J.-F. Masson and P. Chaurand* Analytical Chemistry, Vol. 88, 6018–6025 (2016). DOI 10.1021/acs.analchem.6b01141HTML
- Assessment of pathological response to therapy using lipid mass spectrometry imaging. N.H. Patterson*, B. Alabdulkarim, A. Lazaris, A. Thomas*, M.M. Marcinkiewicz, Z. Gao, P.B. Vermeulen, P. Chaurand* and P. Metrakos. Scientific Reports, Vol. 6, 36814 (2016). DOI 10.1038/srep36814HTML
2015
- Increasing Specificity in Imaging Mass Spectrometry: High Spatial Fidelity Transfer of Proteins from Tissue Sections to Functionalized Surfaces. E. Fournaise* and P. Chaurand*. Analytical and Bioanalytical Chemistry, Vol. 407, 2159-2166 (2015). DOI 10.1007/s00216-014-8300-zHTML
- In Search of the Molecular Mechanisms Mediating the Inhibitory Effect of the GnRH Antagonist Degarelix on Human Prostate Cell Growth. M. Sakai, D.B Martinez-Arguelles, N.H Patterson*, P. Chaurand* and V. Papadopoulos. PLoS ONE, Vol. 10(3): e0120670 (2015). DOI 10.1371/journal.pone.0120670HTML
- Development of Alternative Laser Desorption Imaging Mass Spectrometry Methods to Investigate the Molecular Composition of Latent Fingermarks. N. Lauzon*, M. Dufresne*, V. Chauhan and P. Chaurand*. Journal of the American Society for Mass Spectrometry, Vol. 26, 878-886 (2015). DOI 10.1007/s13361-015-1123-0HTML
- Acute Amnestic Encephalopathy in Amyloid-ß Oligomers Injected Mice is Due to Their Widespread Diffusion in Vivo. S. Epelbaum, I. Youssef, P.N. Lacor, P. Chaurand*, E. Duplus, B. Brugg, C. Duyckaerts and B. Delatour. Neurobiology of Aging, Vol. 36, 2043-2052 (2015). DOI 10.1016/j.neurobiolaging.2015.03.005HTML
- Aberrant Lipid Metabolism in the Forebrain Niche Suppresses Adult Neural Stem Cell Proliferation in an Animal Model of Alzheimer’s Disease. L.K. Hamilton, M. Dufresne*, S.E. Joppe, A. Aumont, S. Petryszyn, F. Calon, A. Furtos, M. Parent, P. Chaurand* and K.J.L. Fernandes. Cell Stem Cell, Vol. 17, 397-411 (2015). DOI 10.1016/j.stem.2015.08.001HTML
2014
- Advances in Tissue Section Preparation for MALDI Imaging Mass Spectrometry. A. Thomas* and P. Chaurand*. Bioanalysis, Vol. 6, 967-982 (2014). DOI 10.4155/BIO.14.63HTML
- Monitoring Time-dependent Degradation of Phospholipids in Sectioned Tissues by MALDI Imaging Mass Spectrometry. N.H. Patterson*, A. Thomas* and P. Chaurand*. Journal of Mass Spectrometry, Vol. 49, 622-627 (2014). DOI 10.1002/jms.3382HTML
- Acyl-Coenzyme A Binding Protein Regulates Beta Oxidation Required for Growth and Survival of Non-Small Cell Lung Cancer. F.T. Harris, S.M.J. Rahman, M. Hassanein, J. Qian, M.D. Hoeksema, X. Ji, H. Chen, R. Eisenberg, P. Chaurand*, R.M. Caprioli, M. Shiota, and P.P. Massion. Cancer Prevention Research, Vol. 7, 748-757 (2014). DOI 10.1158/1940-6207.CAPR-14-0057HTML
- Unravelling Nonspecific Adsorption of Complex Protein Mixture on Surfaces with SPR and MS. J. Breault-Turcot, P. Chaurand* and J-F. Masson. Analytical Chemistry, Vol. 86, 9612-9619 (2014). DOI 10.1021/ac502077bHTML
2013
- Orthogonal Organic and Aqueous-based Washes of Tissue Sections to Enhance Protein Sensitivity by MALDI Imaging Mass Spectrometry. A. Thomas*, N.H. Patterson*, J. Laveaux Charbonneau* and P. Chaurand*. Journal of Mass Spectrometry, Vol. 48, 42-48 (2013). DOI 10.1002/jms.3114HTML
- Histology-driven Data Mining of Lipid Signature from Multiple Imaging Mass Spectrometry Analyses: Application to Human Colorectal Cancer Liver Metastasis Biopsies. A. Thomas*, N.H. Patterson*, M. Marcinkiewicz, A. Lazaris, P. Metrakos and P. Chaurand*. Analytical Chemistry, Vol. 85, 2860-2866 (2013). DOI 10.1021/ac3034294HTML
- Silver Assisted Laser Desorption Ionization for High Spatial Resolution Imaging Mass Spectrometry of Olefins from Thin Tissue Sections. M. Dufresne*, A. Thomas*, J. Breault-Turcot, J-F. Masson and P. Chaurand*. Analytical Chemistry, Vol. 85, 3318-3324 (2013). DOI 10.1021/ac3037415HTML
- Nonspecific Adsorption of Crude Cell Lysate on SPR Sensors. A. Aube, J. Breault-Turcot, P. Chaurand*, J. Pelletier and J-F. Masson. Langmuir, Vol. 29, 10141-10148 (2013). DOI 10.1021/la401837yHTML
2012
- Sublimation of New Matrix Candidates for High Spatial Resolution Imaging Mass Spectrometry of Lipids: Enhanced Information in Both Positive and Negative Polarities After 1,5-diaminonapthalene Deposition. A. Thomas, J. Laveaux Charbonneau, E. Fournaise and P. Chaurand*. Analytical Chemistry, Vol. 84, 2048-2054 (2012). DOI 10.1021/ac2033547HTML
- Activity-Based Probes linked with Laser-Cleavable Reporter Tags for Signal Amplification in Imaging Mass Spectrometry: Analysis of Serine Hydrolase Enzymes in Mammalian Tissue. J. Yang, P. Chaurand*, J.L. Norris, N.A. Porter and R.M. Caprioli. Analytical Chemistry, Vol. 84, 3689-3695 (2012). DOI 10.1021/ac300203vHTML
- Imaging Mass Spectrometry of Thin Tissue Sections: A Decade of Collective Efforts. P. Chaurand*. Journal of Proteomics, Vol. 75, 4883-4892 (2012). DOI 10.1016/j.jprot.2012.04.005HTML
2011
- Advances in Proteomics Strategies Towards the Early Detection of Lung Cancer. M. Hassanein, S.M.J. Rahman, P. Chaurand* and P.P. Massion. Proceedings of the American Thoracic Society, Vol. 8, 183-188 (2011). DOI 10.1513/pats.201012-069MSHTML
- Mass Spectrometry for the Evaluation of Cardiovascular Diseases Based on Proteomics and Lipidomics. A. Thomas*, S. Lenglet, P. Chaurand*, J. Deglon, P. Mangin, F. Mach, S. Steffens, J-L. Wolfender and C. Staub. Thrombosis & Haemostasis, Vol. 106, 20-33 (2011). DOI 10.1160/TH10-12-0812HTML
- Properties of Ionic Liquids on Au Surfaces: Non-conventional Anion Exchange Reactions with Carbonate. M. Ratel, M. Branca, J. Breault-Turcot, S.S. Zhao, P. Chaurand*, A.R. Shmitzer and J-F. Masson. Chemical Communications, Vol. 47, 10644-10646 (2011). DOI 10.1039/c1cc13914bHTML
- MALDI Imaging Mass Spectrometry: A Promising Technique in Reproductive Research. M. Lagarrigue, R. Lavigne, B. Guevel, E. Com, P. Chaurand* and C. Pineau. Biology of Reproduction. Vol. 86(3)74, 1-11 (2011). DOI https://doi.org/10.1095/biolreprod.111.094896HTML
Non Peer-reviewed Publications
2015
- Congratulations Professor Caprioli! E. Gelpi, P. Chaurand*, M. Linscheid, T. Nakamura, Y. Wada, W. Korfmacher, F. Turecek, M.N. Eberlin and K. Vekey. Journal of Mass Spectrometry, Vol. 49, 1203-1204 (2015). HTML
- Introducing Specificity and Sensitivity in Imaging Mass Spectrometry. P. Chaurand*. Bioanalysis, Vol. 7, 2279-2294 (2015). HTML
2014
- Monitoring Time-Dependent Degradation of Phospholipids in Sectioned Tissues by MALDI Imaging Mass Spectrometry. N.H. Patterso*n, A. Thomas* and P. Chaurand*. Spectroscopy Solutions. October 2014. HTML
2011
- Imaging Mass Spectrometry: Current Performances and Upcoming Challenges. P. Chaurand*. Current Trends in Mass Spectrometry, supplement to Spectroscopy and LCGC North America, 30-37 (July 2011) HTML
Book Chapters
2021
- Metal-Assisted LDI Imaging MS for Biological and Forensic Applications. F. Fournelle* and P. Chaurand* Methods in Molecular Biology, Mass Spectrometry Imaging of Small Molecules. (Ed. Y-J. Lee), Humana Press. 2021, pp 99-115.
- MALDI mass spectrometry imaging - past, present and future challenges. P. Chaurand. MALDI MS Imaging: From Fundamentals to Spatial Omics. (Ed. Tiffany Porta Siegel), Royal Society of Chemistry. 2021, pp 20-38.
2017
- Assessing the Potential of Metal-Assisted Imaging Mass Spectrometry in Cancer Research. M. Dufresne*, N.H. Patterson*, N. Lauzon* and P. Chaurand* Advances in Cancer Research, Vol. 134, 67-84 (2017) HTML
2016
- (MA)LDI MS Imaging Mass Spectrometry at High Specificity and Sensitivity. A. Thomas*, N.H. Patterson*, M. Dufresne* and P. Chaurand*. Advances in MALDI and laser-induced soft ionization mass spectrometry. (Ed. Rainer Cramer), Springer International Publishing Switzerland, 2016, pp 129-147. 9. HTML
2014
- Impact de L’imagerie Moléculaire par Spectrométrie de Masse dans L’étude de la Maladie d’Alzheimer. P. Chaurand*. Vieillissement et démences. Un défi médical, scientifique et socio-économique. Rapport de l’Académie Nationale de Médecine. (Eds. J-P. Tillement, J-J. Hauw, V. Papadopoulos), Lavoisier, Paris, 2014, pp 37-40. HTML